Annexon, Inc. is a clinical-stage biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. It identifies and characterizes the role of the classical complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology, using its proprietary platform. Its lead candidate, ANX005, an investigational, full-length monoclonal antibody (mAb), is formulated for intravenous administration as the potential first targeted treatment for patients with Guillain-Barre Syndrome (GBS). It is advancing ANX1502, a novel small-molecule inhibitor of classical complement designed for oral administration in a range of chronic autoimmune diseases. It is also advancing ANX007, designed to block C1q locally in the eye, to provide complete protection against excess classical complement activity and the loss of photoreceptor neurons.
Company Information
About this company
Key people
Douglas E. Love
President, Chief Executive Officer, Director
Jennifer Lew
Chief Financial Officer, Executive Vice President
Dean Rick Artis
Executive Vice President, Chief Scientific Officer
Jamie Dananberg
Executive Vice President, Chief Medical Officer
Michael Overdorf
Executive Vice President, Chief Business Officer
Ted Yednock
Executive Vice President, Chief Innovation Officer
Thomas G. Wiggans
Independent Chairman of the Board
William H. Carson
Independent Director
Jung E. Choi
Independent Director
Bettina M. Cockroft
Independent Director
William Jones
Independent Director
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Key facts
- Shares in issue144.55m
- EPICANNX
- ISINUS03589W1027
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$873.06m
- Employees99
- ExchangeNASDAQ
- Index
- Website
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