Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in harnessing the power of human genetics and variant functionalization with its Maze Compass platform to develop small-molecule precision medicines for the treatment of renal, cardiovascular and related metabolic diseases, including obesity. The Compass platform has been purpose-built to inform all phases of drug discovery and development process through clinical trial design, advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach to chronic kidney disease (CKD). Its lead program, MZE829, is an oral, small-molecule inhibitor of apolipoprotein L1, or APOL1, for the treatment of patients with APOL1 kidney disease, or AKD. Its second lead program, MZE782, is an oral, small-molecule inhibitor of the solute transporter SLC6A19, a novel CKD target.
Company Information
About this company
Key people
Herve Hoppenot
Chairman of the Board
Jason V. Coloma
Chief Executive Officer, Director
Charles Homcy
Co-Founder, Director
Misbah Tahir
Chief Financial Officer and Principal Financial Officer
Courtney J. Phillips
General Counsel, Corporate Secretary
Harold Bernstein
President - Research and Development, Chief Medical Officer
Atul Dandekar
Chief Strategy and Business Officer
Nancy C. Andrews
Independent Director
Jamie Brush
Independent Director
Alan B. Colowick
Independent Director
Neil Exter
Independent Director Nominee
Sekar Kathiresan
Independent Director
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Key facts
- Shares in issue48.12m
- EPICMAZE
- ISINUS5787841007
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$2.32bn
- Employees125
- ExchangeNASDAQ
- Index
- Website
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