Revolution Medicines, Inc. is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The Company's research and development pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The Company is advancing a pipeline of RAS(ON) Inhibitors, daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor are in clinical development. The Company's pipeline also focus on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C). The Daraxonrasib, our RAS(ON) multi-selective inhibitor, is designed as an oral, tri-complex inhibitor of multiple RAS(ON) variants containing cancer driver mutations at all three of the major RAS mutation hotspot positions, G12, G13, and Q61.
Company Information
About this company
Key people
Mark A. Goldsmith
Chairman of the Board, President, Chief Executive Officer
Flavia Borellini
Independent Director
Franklin K. Clyburn
Independent Director
Sandra J. Horning
Independent Director
Jack Lee Anders
Senior Vice President - Finance, Principal Accounting Officer
Stephen M. Kelsey
President - Research and Development
Margaret A. Horn
Chief Operating Officer
Jeffrey Cislini
Senior Vice President, General Counsel, Secretary
Anthony Mancini
Chief Global Commercialization Officer
Alan Sandler
Chief Development Officer
Alexis A. Borisy
Lead Independent Director
Elizabeth McKee Anderson
Independent Director
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Key facts
- Shares in issue212.60m
- EPICRVMD
- ISINUS76155X1000
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$32.71bn
- Employees883
- ExchangeNASDAQ
- IndexTR Equity United States Index
- Website
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