Rezolute, Inc. is a late-stage rare disease company, which is focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, Ersodetug (formerly RZ358), is a potential treatment for hypoglycemia caused by multiple forms of hyperinsulinism including congenital HI and tumor HI. Ersodetug is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat, and muscle. Congenital is a rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas. RZ402, which is an oral plasma kallikrein inhibitor (PKI) being developed as a potential therapy for the chronic treatment of diabetic macular edema (DME). DME is a vascular complication of diabetes and a leading cause of blindness. RZ402 is designed to block bradykinin production and its resulting effects on vascular leakage and inflammation.
Company Information
About this company
Key people
Nevan Charles Elam
Acting Chairman of the Board, Chief Executive Officer
Daron Evans
Chief Financial Officer
Sunil Karnawat
Chief Commercial Officer
Brian K. Roberts
Chief Medical Officer
Young-Jin Kim
Director
Philippe Fauchet
Independent Director
Erik Harris
Independent Director
Wladimir Hogenhuis
Independent Director
Nerissa C. Kreher
Independent Director
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Key facts
- Shares in issue92.73m
- EPICRZLT
- ISINUS76200L3096
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$280.04m
- Employees71
- ExchangeNASDAQ
- IndexTR Equity United States Index
- Website
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