Tectonic Therapeutic, Inc. is a clinical-stage biotechnology company. The Company is focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs). Its technology platform called GEODe (GPCRs Engineered for Optimal Discovery), is focused on developing biologic medicines that overcome the existing challenges of GPCR-targeted drug discovery and harness the human body to modify the course of disease. Its product candidates are TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone relaxin. Its second development candidate, TX2100, is a VHH-Fc fusion antagonist antibody that binds to the APJ receptor (APLNR), also known as the apelin receptor. Its APJ is a differentiated approach for the treatment of hereditary hemorrhagic telangiectasia (HHT) and is a selective anti-angiogenic target that is primarily expressed in endothelial cells.
Company Information
About this company
Key people
Francois Nader
Independent Chairman of the Board
Praveen P. Tipirneni
Independent Director
Alise S. Reicin
President, Chief Executive Officer, Director
Daniel Lochner
Chief Financial Officer
Peter Mcnamara
Chief Scientific Officer
Marcella Kuhlman Ruddy
Chief Medical Officer
Marc Schwabish
Chief Business Officer
Phillip B. Donenberg
Independent Director
Terrance G. McGuire
Independent Director
Timothy A. Springer
Independent Director
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Key facts
- Shares in issue18.78m
- EPICTECX
- ISINUS8789721086
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$562.36m
- Employees60
- ExchangeNASDAQ
- Index
- Website
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