Amylyx Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company. The Company is focused on three investigational therapies across several neurodegenerative and endocrine diseases. Its lead investigational asset is avexitide, an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist. Avexitide has been evaluated as a treatment for Post-Bariatric Hypoglycemia (PBH) and congenital HI, two indications characterized by hyperinsulinemic hypoglycemia. In addition to avexitide, it is advancing AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol in Wolfram syndrome and progressive supranuclear palsy (PSP), and AMX0114 in amyotrophic lateral sclerosis (ALS). AMX0035 is designed to mitigate neurodegeneration by targeting endoplasmic reticulum stress and mitochondrial dysfunction, two cellular processes central to neuronal cell death and neurodegeneration. AMX0114 is an investigational antisense oligonucleotide.
Company Information
About this company
Key people
Joshua B. Cohen
Co-Chief Executive Officer, Director
Justin Klee
Co-Chief Executive Officer, Director
James M. Frates
Chief Financial Officer
Gina M. Mazzariello
Chief Legal Officer and General Counsel
Camille L. Bedrosian
Chief Medical Officer
George Mclean Milne
Chair of the Board of Directors
Karen M. Firestone
Independent Director
Paul Fonteyne
Independent Director
Daphne E. Quimi
Independent Director
Bernhardt Zeiher
Independent Director
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Key facts
- Shares in issue109.82m
- EPICAMLX
- ISINUS03237H1014
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$1.38bn
- Employees123
- ExchangeNASDAQ
- IndexTR Equity United States Index
- Website
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