Ardelyx, Inc. is a commercial-stage biopharmaceutical company focused on the development and commercialization of innovative medicines that meet significant unmet medical need. The Company markets two therapies from the active ingredient tenapanor, a sodium/hydrogen exchanger (NHE3) inhibitor. NHE3 is an antiporter expressed on the apical surface of the small and large intestines. Tenapanor is a minimally absorbed, first-in-class, oral, small molecule therapy. Tenapanor, branded as IBSRELA, is approved in the United States for the treatment of adults with irritable bowel syndrome with constipation. Tenapanor, branded as XPHOZAH, is approved in the United States to reduce serum phosphorus in adults with chronic kidney disease on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy. In addition to commercializing IBSRELA and XPHOZAH, it is also developing a next-generation NHE3 inhibitor.
Company Information
About this company
Key people
David M. Mott
Independent Chairman of the Board
Robert B. Bazemore
Independent Director
William C. Bertrand
Independent Director
Muna Bhanji
Independent Director
Onaiza Cadoret - Manier
Independent Director
Michael G. Raab
President, Chief Executive Officer, Director
Sue Hohenleitner
Chief Financial Officer
James P. Brady
Chief Human Resources Officer
John E. Bishop
Chief Technical and Quality Officer
Rajani Dinavahi
Chief Medical Officer
Felecia Ettenberg
Chief Legal Officer
Eric Foster
Chief Commercial Officer
Michael Kelliher
Chief Business Officer
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Key facts
- Shares in issue247.03m
- EPICARDX
- ISINUS0396971071
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$1.53bn
- Employees489
- ExchangeNASDAQ
- IndexTR Equity United States Index
- Website
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