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Eli Lilly (Q4 Results): beats on earnings and guidance

Eli Lilly’s strong sales momentum carried over into the final quarter of 2025, and it’s set to do the same this year.
Pharmaceutical laboratory- Eli Lilly-share-research

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Eli Lilly’s fourth-quarter revenue grew 43% to $19.3bn (consensus $18.0bn) driven by volume growth in its best sellers, Mounjaro and Zepbound.

Underlying operating profit was up 52% to $8.6bn as revenue growth outpaced cost expansion.

2026 sales are expected land in the $80bn-$83bn range, reflecting growth of 25% at the mid-point and better than consensus forecasts. Underlying earnings per share guidance stands at $33.50-$35.00, implying growth of about 41%.

The shares rose 7.8% in early trading.

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HL view to follow.

Eli Lilly key facts

All ratios are sourced from LSEG Datastream, based on previous day’s closing values. Please remember yields are variable and not a reliable indicator of future income. Keep in mind key figures shouldn’t be looked at on their own – it’s important to understand the big picture.

This article is original Hargreaves Lansdown content, published by Hargreaves Lansdown. It was correct as at the date of publication, and our views may have changed since then. Unless otherwise stated estimates, including prospective yields, are a consensus of analyst forecasts provided by LSEG. These estimates are not a reliable indicator of future performance. Yields are variable and not guaranteed. Investments rise and fall in value so investors could make a loss.

This article is not advice or a recommendation to buy, sell or hold any investment. No view is given on the present or future value or price of any investment, and investors should form their own view on any proposed investment.

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Written by
Derren Nathan
Derren Nathan
Head of Equity Research

Derren leads our Equity Research team with more than 15 years of experience in his field. Thriving in a passionate environment, Derren finds motivation in intellectual challenges and exploring diverse ideas within his writing.

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Article history
Published: 4th February 2026